Patrick Mahomes and the two-time defending AFC champion Kansas City Chiefs are the last undefeated team standing in the AFC, and they'll look to keep it that way against the New Orleans Saints this week on "Monday Night Football."

Kansas City has won 10 straight games dating back to last season, including the playoffs. The four wins this season have all come by one possession, with the Chiefs either needing a late score or stop to seal a win.

The Saints have cooled after a monster offensive start to the season. After blasting through its first two opponents and scoring 91 points in wins against the Panthers and Cowboys, New Orleans has lost its last two, and scored a more pedestrian 12 (against the Eagles) and 24 points (against the Falcons) in those two losses. Still, the Saints are a solid rushing offense led by a resurgent Alvin Kamara, who is tied for the league lead with five rushing touchdowns.

The Chiefs' defense — not their Patrick Mahomes-led offense — has been the strength of this team through a 4-0 start. That continues to hold true early against the Saints.

The Chiefs took over on a sensational interception by safety Bryan Cook. Derek Carr throws a deep ball up for grabs under pressure on first down, and Cook comes up with it for a turnover on the first drive of the game.

The Chiefs convert the turnover into a 10-play, 78-yard drive capped by a 5-yard Kareem Hunt touchdown run. 7-0 Chiefs, and a brutal start for the Saints.

The Saints go 3-and-out on their second possession and punt. This could spiral quickly for New Orleans.

Saints safety Will Harris limped off the field after appearing to suffer a non-contact leg injury. He was down on the Chiefs sideline for an extended period before walking to the locker room.

Derek Carr has been under constant pressure from Steve Spagnuolo's defense to great success for Kansas City.

The Saints are finally moving the ball. Multiple first downs on this drive, and they're over midfield.

The Saints cap the drive with a deep ball from Derek Carr to Rashid Shaheed for a 43-yard touchdown. Shaheed takes the top off the defense, and Carr finds him running free toward the end zone. 10-7, Chiefs.

The Saints defense forces a 3-and-out and a Chiefs punt for a big early stop. A second Chiefs score in two possessions would've spelled trouble for the Saints.

The Saints force an incompletion on fourth-and-5 in the red zone. Chiefs opt for a field goal and take a 10-0 lead.

Kansas City's defense comes up with another stop, forcing a second-straight 3-and-out from the Saints. That's an interception and two 3-and-outs on three Saints possessions.

The Chiefs' defense has been the strength of this team through a 4-0 start. That continues to hold true early against the Saints.

A sack of Patrick Mahomes puts the Chiefs in third-and-14 and ultimately forces Kansas City to settle for a field goal. Harrison Butker coverts from 34 yards, and the Chiefs extend their lead to 13-7 with 1:32 remaining before halftime.

And now the Chiefs have a first down. They ended up in second-and-34 after a holding penalty. On third-and-22, Travis Kelce caught a pass from Patrick Mahomes on a crossing route, then lateraled the ball to Samaje Perine.

Perine then carried the ball two yards short of the sticks. The Chiefs went for it on fourth-and-2 and converted. What a play.

Alontae Taylor just blew up a Chiefs play in the backfield and potentially short-circuited a Kansas City drive that had moved into Saints territory. Put Kansas City in second-and-24. Chiefs running back Carson Steele lost the ball a week after a fumble landed him on the bench. Xaiver Worthy recovered for the Chiefs.

The Kansas City Chiefs have relied heavily on their defense early in the season, winning four straight one-score games. They are 5.5-point home favorites against the New Orleans Saints on Monday Night Football in the Week 5 NFL odds, as New Orleans tries to snap a two-game losing streak. Chiefs quarterback Patrick Mahomes is playing without wide receiver Rashee Rice (knee) and Marquise Brown (shoulder), leaving tight end Travis Kelce and rookie Xavier Worthy as his top targets. Worthy only has nine catches through four games, but his over/under for receptions on Monday is 3.5 in the Saints vs. Chiefs prop odds.

Kelce, who was targeted a season-high nine times in a win over the Chargers last week, has an over/under of 5.5 receptions in the MNF prop odds. Should you back Kelce to have a big game with your Saints vs. Chiefs bets? Before betting any NFL props for Monday Night Football or entering NFL predictions on sites like PrizePicks, you need to see the Chiefs vs. Saints NFL prop predictions powered by SportsLine's AI PickBot.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each player prop. The AI predictions are determined by statistically learning from each player's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score.

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. Last season, the AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. This year, it has already nailed 128 picks rated 4 stars or better. Anybody who followed those picks was way up.

For Chiefs vs. Saints NFL betting on Monday Night Football, the AI PickBot has evaluated the NFL player prop odds and provided Saints vs. Chiefs prop picks for every available prop market. You can only see the AI player prop predictions for Kanas City vs. New Orleans here.

After analyzing Chiefs vs. Saints props and examining the dozens of NFL player prop markets, the AI PickBot says Saints quarterback Derek Carr goes under 213.5 passing yards. Kansas City's defense has held three of its first four opponents to 20 points or fewer, and New Orleans has cooled off offensively following a high-flying start. Carr has attempted 25 passes or less in three of his first four games, finishing with just 142 passing yards against Philadelphia two weeks ago.

He has also thrown an interception in three straight games and will be playing in front of a hostile crowd on Monday night. The AI PickBot expects New Orleans to try to diffuse that situation by giving running back Alvin Kamara a heavy dose of touches, which will keep the clock running and limit Carr's total opportunities. He is finishing with 200.3 passing yards in the latest projections, creating plenty of value on the Under (213.5) as a 4-star pick. See more NFL props here.

In addition, the AI PickBot says one star sails past his rushing total and has five other NFL props rated 4 stars or better. You need to see the AI PickBot's analysis before making any Saints vs. Chiefs prop bets for Monday Night Football.

Which Chiefs vs. Saints prop bets should you target for Monday Night Football? Visit SportsLine now to see the top Saints vs. Chiefs props, all from the SportsLine AI PickBot that nailed 1,674 top-rated picks last season and has hit 128 picks this year.