The Week 4 college football schedule on Friday features an ACC matchup kicking things off as the Stanford Cardinal (1-1) and the Syracuse Orange (2-0) link up. In 2023, Syracuse went 3-1-1 ATS as the favorite. Meanwhile, the Cardinal were 2-2 as the away underdog. Both teams are 1-1 against the spread this season

Kickoff from JMA Wireless Dome in Syracuse, NY., is 7:30 p.m. ET. After opening at -10.5, the Orange are 9.5-point favorites in the latest Stanford vs. Syracuse odds via SportsLine consensus, while the over/under for total points scored is 56.5. Before making any Syracuse vs. Stanford picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

SportsLine's Proven Model

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 5-2 start on over/under picks this season. Anyone who has followed it has seen strong returns!

Now, the model has dialed in on Stanford vs. Syracuse and just revealed its coveted picks and predictions. You can head to SportsLine now to see the model's picks. Here are the college football odds on the spread, money line and over/under for Syracuse vs. Stanford:

Key Players to Watch

Syracuse Orange

Syracuse has an array of difference-makers on offense to help out quarterback Kyle McCord. At running back, junior LeQuint Allen is the main option. Allen has impressive contact balance and runs with intention. In two games, the New Jersey native has 30 rushes for 181 yards and six yards per carry. In his last outing, Allen had 83 rushing yards, three receptions and 47 yards.

Junior tight end Oronde Gadsden II is a big-bodied pass catcher who has legit hands to snag passes. He's first on the team in catches (13) and rushing yards (201) with three touchdowns. In the win over Georgia Tech, Gadsden II had six receptions for 93 yards and two scores. Junior running back Trebor Pena is an additional threat in the passing game. He has 12 catches for 166 yards and four touchdowns. See who to back at SportsLine.

Stanford Cardinal

The Cardinal will need their defense ready to play in this tilt. Through two games, they are allowing a conference-low 64.5 rushing yards per game with 20.5 points per game. Junior safety Jay Green is a reliable defender who plays with impressive awareness in both phases. Green has 12 total tackles and one forced fumble.

Senior linebacker Gaethan Bernadel is seemingly always in on the play, leading the team in total tackles with 16. He's finished with at least six total stops in consecutive games. Senior linebacker Tristan Sinclair joins Bernadel in the middle of the field. Sinclair is a sure tackler who has a knack for finding the ball carrier. He has 11 total tackles and one sack on the season. See who to back at SportsLine.

Expert Predictions

SportsLine's model is leaning Under on the total, projecting 52 points. It also says one side of the spread hits well over 50% of the time. You can see the model's pick at SportsLine.

So who wins Stanford vs. Syracuse, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on top-rated spread picks since its inception, and find out.