The Los Angeles Rams' offensive woes continued Sunday at State Farm Stadium in Glendale, Arizona, as they suffered a humiliating 41-10 defeat to the Arizona Cardinals. But the Rams' struggles on the field were compounded by an injury to one of their most important offensive players, wide receiver Cooper Kupp.

Kupp injured his ankle in the second quarter of the game and did not return. He was seen leaving the locker room after the game wearing a walking boot on his left foot. Rams coach Sean McVay said after the game that he did not have an update on the severity of Kupp's injury.

The injury to Kupp is a significant blow to the Rams, who are already without wide receiver Puka Nacua, who is on injured reserve after spraining his posterior cruciate ligament in Week 1. The Rams are reportedly expecting Nacua to miss between five and seven weeks.

Without Kupp and Nacua, the Rams are extremely thin at wide receiver. Behind Kupp and Nacua, the Rams have wide receivers Demarcus Robinson, Tyler Johnson, Tutu Atwell, and rookie sixth-round pick Jordan Whittington.

Kupp appeared to sustain the injury on his fourth reception of the game, a 24-yard catch-and-run near the end of the first half. He walked off the field to the locker room at halftime with a noticeable limp.

It is unclear how long Kupp will be sidelined. However, the Rams are facing a daunting task without him, as they are already 0-2 and will face the San Francisco 49ers next week.

Kupp's absence is a major loss for the Rams' offense, as he is one of the most dynamic players in the league. In his first two games this season, he had 18 catches for 147 yards and a touchdown.

The Rams will need to find a way to replace Kupp's production if they want to be competitive this season. The Rams are already facing an uphill battle, as they have been plagued by injuries and have struggled to find consistency on both sides of the ball.

The Rams' struggles on offense were evident in their loss to the Cardinals. Quarterback Matthew Stafford did not throw a touchdown pass for the first time since Week 1 of the 2023 season. His streak of 15 consecutive starts with a passing touchdown had been the second-longest active streak in the NFL behind Atlanta Falcons quarterback Kirk Cousins.

The Rams' defense also struggled against the Cardinals, giving up 489 yards of offense, including 231 rushing yards. The Cardinals were able to take advantage of the Rams' struggles on defense, scoring touchdowns on their first three possessions of the game.

The Rams' defense is without future Hall of Famer Aaron Donald, who retired in March.

The Rams will need to find a way to improve on both sides of the ball if they want to turn their season around. However, the loss of Kupp is a setback that could make that task even more difficult.

The Rams have allowed 67 points in two games, their third most through two games of a season in franchise history.

The Rams' loss to the Cardinals is a bad omen for the Rams, who are trying to bounce back from a disappointing 2023 season. The Rams are now 0-2 for the first time under McVay and the first time since the 2011 season.

With the Rams now 0-2, their hopes of making a playoff run are already in jeopardy.

The Rams will need to find a way to get back on track if they want to avoid another disappointing season. They will have a chance to do so next week when they face the 49ers.

Looking Ahead: Rams vs. 49ers

The Rams will host the 49ers next week at SoFi Stadium. The 49ers are one of the best teams in the NFL, and the Rams will need to be at their best to pull off an upset.

The 49ers are coming off a Week 2 win over the Atlanta Falcons, and they are poised to make a deep run in the playoffs this season.

The 49ers have a potent offense that is led by quarterback Brock Purdy and wide receiver Deebo Samuel. The 49ers also have a strong defense that is led by linebacker Fred Warner.

The Rams will have their work cut out for them against the 49ers. However, if they can get healthy and improve their play, they will have a chance to pull off an upset.

Will the Rams Be Able to Bounce Back?

The Rams' season is off to a rough start. They are 0-2, they are dealing with injuries, and they have struggled on both sides of the ball.

The Rams have a lot of work to do if they want to turn their season around. However, they have the talent to be a competitive team.

It will be interesting to see how the Rams respond to their Week 2 loss.

Will they be able to bounce back and get back to winning ways?

Only time will tell.